You still haven't indicated what sound card you are using. What error messages are you getting? Did it complete the vst scan on first start up? Did it reprofile your sound card on start up? It sounds like may have a problem with your sound card. Have you checked all the connections? Does your sound card put out sound when using a stand alone plug in? Have you installed any updates recently for plugins/ video card etc?.
Does it only crash when you try to open an existing project or does it not even get to the point where you can select a project to open? Are you using 32bit Sonar or 64bit?
Information is needed before anyone can offer any significant suggestions. I have never run into a problem that required a reinstallation of Sonar. Any problems I have had have usually resulted from updates, installation of new hardware that is conflicting with existing drivers/hardware, Windows updates, iTunes updates(especially Quicktime) video driver updates, vst updates, and even Internet explorer updates.
Think back to when the problem started and try and remember anything you changed/updated/added to your system just prior to the problem occurring and that might get you pointed in the direction where you can find a solution.