I'm running a test Windows 10 partition and notice there are connectivity issues between VIA firewire and Saffire Pro, as confirmed here:
http://uk.focusrite.com/answerbase/windows-10-compatibility
 
I don't know if other VIA firewire chipsets are effected.
Just a heads up!
 
Thanks...

knock on wood... i have a VIA VT6308 chip in my Gigabyte mobo and my Saffire Pro 24 has worked so far.  Seems like my chips is one recommended in their document below...
 
focusrite has an app on their site that will analyze your chipset and give advice on it...
http://us.focusrite.com/a...h-my-interface?id=1184
 
here is their pdf that talks about acceptable firewire devices...
http://d3se566zfvnmhf.cloudfront.net/sites/default/files/answerbase/Focusrite%20IEEE%201394%20Compatibility_0.pdf
 
just found out the urls get shortened in the forum... if u rt click on them you will go there... if you copy it it will not work.
 

You are running running 3.4. I'm running 3.6 . Maybe that I the issue.

Btw under Win8.1 at least 3.6 is by far a better driver.

I have had no problems since upgrading to Windows 10 last week.
 
I'm running Windows 10 Pro with Mixcontrol 3.6 downloaded from the Saffire Pro 40 location (although I'm using the Pro 14). The OHCI scan tool reports this:
 
Looking for OHCI 1394 Host Controllers...
1:
Vendor : (1106) VIA Technologies
Chipset: (3044) VT6307/VT6308
Revision: C0
Status : Active
Details:
Subsysten VendorId: 1043
Subsystem DeviceId: 81fe
Max # isoch Rx contexts: 4
Max # isoch Tx contexts: 8
Max 1394 Speed Capability: S400
Support: Compatible, no known issues.
Done.

OHCI shows as compatible on my machine as well. Regardless is a known issue see Focusrite link. Glad it works for some.

Btw I didn't upgrade. This was a clean Win10 install after formatting the hard drive. I do have an upgrade somewhere else I will try that next.

I have Firewire latency set to 'Medium' - 'Short' did not do as well for me.
 

Upgrades don't work either. So that's both clean install and upgrades.
It's definitely the chipset model. Looks like you have a variant that works.
The symptoms are that you can't connect to the interface (as Focusrite explains) so you can't even adjust the settings if you tried.
 
Nevermind my DAW is still on Win8.1

If it helps, here is how my firewire drivers look:
 

DA, the driver on the focusrite website for my Saffire Pro 24 is ver 3.4.  I'm going to stick with it as long as it's working.  

Going back a few years, but wasn't the TI chipset identified as the one to have for Sonar and Firewire? I seem to recall a thread where it was listed as a best practice.