the focusrite preamps definitely do not match the pristine quality of the preamps in the babyface pro i have....
 
i've ab'd them live, and in mixdown..
 
that said, the focusrite sounds good enough as to not matter.
 
but there isn't much of an equivalent to the RME stuff,
and i cannot attest to the focusrite AD/DA conversion, but the RME is perfect.
also, cannot attest to the  focusrite drivers, but the RME has been extremely reliable.
 
have not worked with any of the MOTU stuff,
but that had been second choice to me when i was shopping.
 
 

FocusRite liquid pres are awesome.

Old thread alert Observe low post count of #20. 

guess it's more relevant now, than it was then.

Yes old threat alert. I asked the original question long time ago.
Meanwhile using several MOTU AVB devices networked over LAN. Something I could not do with RME ... had some hickups initially. But meanwhile really happy with setup