From the A49 user manual, knobs, button, pedals and D-Beam can be assigned to control arbitrary CC or aftertouch.
What I have not found are either knobs are encoders or not. They look almost equivalent to the encoder on my A500S... but they are referenced as "knobs" elsewhere.
I would not like to control parameters by A500S encoder, it is perfect for choosing the program and can set the volume once, but it is tiny, has heavy turn and explicit "ticks".