i recomend canalope
its very tasty

That Cakewalk interface was great though wasn't it?  I had the same unit, bought as a package with Sonar Studio 6 and it lasted happily until a year or so ago.  Even then, it was still possible to get working under W10 and a few driver waltzes.
 
It will depend on what you need in terms of channels etc, but in my case I went for the RME BabyFace Pro.  Excellent unit - costly but it does what it's supposed to do.  Never crashes with the DAW (which oddly the Cakewalk unit used to do not infrequently), and it works just as flawlessly with Studio One as you'd expect.

I would recommend to check your UA25ex again. Mine works fine with Windows 10. If it is really really dead, Windows 10 is rather not a blame. One day I will replace mine with ZOOM UAC-2, or Focusrite Scarlet 6i6. Or Antelope Discrete 4 (if GAS hits me hard).

I've used many USB audio interfaces over the years, and the one I'm sticking with now is the Focusrite Scarlett 18i8 second generation. Great sound quality, low latency, MIDI IN/OUT and great free effects bundle offers.
 
Previously I had the Presonus 1820VSL. Great sound quality, but its USB implementation was horrible. Constantly conflicting with other USB devices. But it did come with a version of Studio One, which I installed and discovered totally paled in comparison to Sonar. 
 
I would absolutely not worry about having to match an interface to work a particular DAW.  All interfaces should work with any DAW you use, since a DAW connects with the interface's drivers (usually ASIO). Nothing proprietary at all there. 

Audient ID14..... the pramps and converters are amazing, cant beat the price.

I'm using a UA-25EX on Win 10 with no issues.  What type of problems are you having?
 
Actually, I did have one issue...the Hi Def Audio on my graphics card will interfere with the UA-25EX (SONAR will say it doesn't exist).  The easy fix for this is to disable the Hi Def Audio on the graphics card.

I'd say go with anything RME, depending on how many inputs / outputs and pres you need, etc.   The pres are great, the AD converters are fantastic and the drivers have a stellar reputation.

Hi. If budget allows, I say go for RME. They make excellent products, and support old devices. Perhaps 2nd hand?
On the budget side (as Chuck mentioned), there is the Focusrite 2i4.
All the best.

Presonus/Focusrite

I have a MOTU 828es (and had a MOTU AVB Ultralite before that).  If you don't have an X99 chipset, it works great and the feature set is incredible.