I tend to have different backup stratagies for different data types, sometimes disc image, sometimes file backups so I do not use the "whole PC option". I also feel (maybe wrongly?) that the bigger the backup file the more likley it will corrupt. For projects and other fast changing data I also mirror on my network drive using synctoy in addition to the Acronis backups.
I try to have redundant backups. One to local USB discs and one to a network drive in a different building, the latter is a bit slow but its insurance against theft or other disaster in the studio.
Synctoy does not handle my large Kontakt library collection well, its too big, as it represents my biggest investment so I keep a manual mirror of this on the network drive in addition to the Acronis backups.