I think with synths you can use a similar approach to acoustic instruments. For example if the synth is doing a bass sound then yes it may not be a great idea to record a really wide stereo patch onto a stereo track. You also need to investigate what effects are being used also on say a bass patch. It may sound better with any modulation widening effects removed for example and just recorded onto a mono track. Some synths like the Juno 106 are basically mono except for one effect right at the end of the chain. But it is well worth recording the chorus effect. It is quite unique. As was the ensemble effect in the Roland JP4.
With synth lead sounds mono recording may also apply but then again some leads may sound killer in stereo and it may be well worth recording them that way too.
With mid range sounds eg pads etc then stereo options may be best for sure. Not all synths rely on modulation effects either in order to create a wide sound. Some use the concept of stacking say 4 or 6
(or 32 in the case of the new Kurzweils) layers in order to create the stereo imaging. Layers are panned here there and everywhere. (in Emulators for example individual voices/layers can be panned or modulated in pan position to create the most sublime effects)
It would be seriously silly to ignore an effect like this and record in mono. You would just be missing out on a beautiful wide sound for no good reason.
Don't forget you can always record in stereo and use a plugin like Channel Tools to narrow things down or bring back to mono later on if you feel the need. And if things don’t sum well here then you can try manipulating the phase of one side of the stereo while summing to mono. There will be a point where L and R will sum to mono and still sound robust.
Like all things use your ears and judge. If a synth sound sounds magnificent in stereo, record it that way.
Also you can mix multiple stereo synth outputs to create huge wide effects. What you don't do in these cases is pan every stereo synth output to hard L and hard R. A good trick is to pan some that way but others from hard L to C and others from C to hard right. Others from 10 o'clock to 2 o'clock for example. There are many ways to combine multiple stereo synth sources.