The 15-minute official walkthrough cclarry posted is a good introduction:
youtube.com/watch?v=UAtVGHl1AFM
ETA the manual: vocaloid.com/en/support/download/
Realivox is an "instrument," but better to consider Vocaloid as a synthesizer-sequencer -- a really complex one. It has automation lanes for a number of parameters simulating vocal characteristics: intensity, how open the mouth is, inflection between syllables, formant-shaping, breathiness, growling, and so on. You can have multiple tracks in the program itself, all loaded with different voicebanks. Unlike Realivox, you can type lyrics in plain English -- or Japanese, Chinese, Korean, or Spanish. Vocaloid will convert them into phonemes you can tweak to make the pronunciation more natural. It will even automatically split syllables across notes.
So while it's way more flexible than Realivox, it's always been harder and more time-consuming to achieve a performance-ready sound outside of backing "ah's" and "ooh's". Vocaloid5 is a huge step in the right direction, though.
The other historical issue with Vocaloid in the West is a dearth of voices provided by native English speakers, or voicetypes that an average musician here would find, um, usable. Yamaha's been working on that since v4 with Cyber Diva and Songman, plus there are the new V5 pack-in voicebanks. Third-party V4 banks Dex, Daina, and Ruby are native English as well.