I tend to favour instrument tracks, as I find it convenient not only for treating them as one track, but also I find it easier to swap out synths on the fly.
With the synth rack, I've got the MIDI track, the synth, and the outputs to separate audio tracks to deal with. If I change synths, I've got to re-route everything, which gets in the way of my workflow during writing.
I don't mind having duplicates of synths as I rarely get anywhere near to maxing out CPU or RAM.
Once I'm happy with an instrument track, I usually freeze it so I can treat it solely as audio.
I guess it all depends on your workflow...
If you've got a good idea for your song before you start recording (or a better memory than I have for keeping ideas in your head!), then separating them out will work fine.
I write and record as I go along. Getting ideas down quickly and developing them in the moment is priority for me.