The above hit on everything, I think, but to sum it all up in terms of tension (what you are "fighting" to bend a string):
Thinner strings have less tension than thicker for the same note.
Shorter scale length requires less tension for the same note.
Tuning down lessens the tension on the strings by default.
Acoustic strings are thicker versus electrics for the same notes, so higher tension; but a couple things to also consider:
Heavier strings have better sustain and are louder.
More tension (if rigidly mounted) has better sustain.
Altering a guitar from its designed strings may involve tension rod and/or bridge adjustment, so you can use less tension, but possibly at the expense of string buzzing.