Jyoti,
 
Dear girl, yes, you forked up big time on the advice and the dead are crying from the brimstone pit for justice. There are enough lawyers down there to process the malpractice lawsuits.
 
30 years ago I was pounding rivets into aircraft in some jungle so would not have been able to help much with the medical stuff. Nor could have medical knowledge about the stroke prevention interaction of NSAID's. They knew what you knew. You did what you had to did as per the evolving understanding of the time.
 
Also as per your question, got a good handle on old age and stroke risk increase. Not so much the blood changes but other factors that might just be up your alley.
 
Will get back with these, but I got Kenny begging for mp3's I got to get delivered first.
 
Love to you and all,
 
John
 

John, I'd like your opinion on my morning regimen. I'm taking meloxicam, curcumin, cayenne, cinnamon, glucosamine chondroitin, and armor thyroid. I usually follow up with a couple Tylenol after a couple hours. Any red flags? Thank you so much for your advice!

Leadfoot,
Will get back with you on this. No major flags but a couple timing issues to be aware of.
John

Leadfoot,
 
Just make sure to take the thyroid supplement about an hour before food in the morning otherwise up to half of the dose is not absorbed. There are a couple yoga postures called the "fish" in conjunction with either the "rabbit" or the shoulderstand that can revitalize connections to the brain and functions of the thyroid and parathyroid. This can over a couple months result in a reduction or even elimination for the need of the T3/T4 supplement.
 
The jury is out on curcumin because of negligible absorption, water insolubility and the rapid metabolic breakdown of what little is absorbed. Almost all of it just passes through the system unprocessed. There is no doubt regarding the benefits of turmeric, either powder or the raw root (plus way less expensive). Personal testimonies about the benefits of the curcumin chemical are out there, but at the same time there are controlled studies that show no benefit once the chemical is refined out of its natural context. This happens so often when we find a plant that has some health benefit. We identify something we think is responsible, extract or manufacture the chemical only to find that the effect is either reduced or in cases harmful. Not as often works the other way though to be fair. Plant extract may be harmful but the extract is safe.
 
Your regimen looks okay.
 
Jyoti, will get back with you on the connection between blood, age, aspirin, cholesterol.
 
John
 

Wow I guess I was misled... I thought I WAS taking turmeric. I thought the curcumin was the good stuff in turmeric. Thank you so much for that clarification, John! I'm buying some real turmeric today!

EDIT: I just ordered a 2lb bag of turmeric powder. Thanks again for the info John!

Curcumin is a major chemical in turmeric and responsible for the bright yellow color. Problem often is that the chemical may or may not be the actual beneficial element, and often the benefit is there because of many other chemicals together in the mix of the native plant. We know very little about many of these and call them "alkaloids" which means we recognize that there is some volatile substance but may not have a clue about what it does or what it is there for.
 
Sad political/economic curse of natural plant research is that it costs a lot of money to do it right and you can't put a patent on a plant, unlike a prescription drug that has a couple decades of a patent allowing the researcher sole receipt of the profits. You do a study to find the effects of loco weed and the guy next door starts selling it using your data. Not a lot of incentive to come up with a ground breaking discovery outside of a college chemistry project.

Jyoti,
 
Have some more info on this but wanted to get back briefly on why your patients were dropping dead of a stroke by mixing their ibuprofen with aspirin.
 
Platelet components in the blood respond to signals that you are bleeding and jump in to do damage control. They morph in seconds from small smooth discs to gargoyles with tendrils, the purpose of which to get entangled with each other and form a temporary plug while the rest of the clotting cascade kicks in. The clot in the flowing bloodstream flows merrily along thru progressively smaller passages until the mess gets stuck shutting off blood supply.  Everything downstream rots in minutes leading to death or tragic injury that may be permanent.
 
The trigger receptor on the platelet needed to start the process is blocked by aspirin locking onto the site. Ibuprofen does the same, so does naproxen, the other NSAID’s to different degrees.
 
Aspirin binds in a “covalent” link, permanent for the life of the bound platelet. Ibuprofen does the same thing but in the nature of a weak atomic bond that is temporary. The naproxen molecule binds to the platelet site and in awhile drifts off. The platelet revives ready to form a clot.
 
If aspirin for stroke protection and ibuprofen for a sprained knee are in circulation at the same time, ibuprofen will bind and aspirin will bypass because the site is already occupied. Aspirin is metabolized/excreted. Ibuprofen drifts off and the platelet wakes up. If aspirin had been there, the platelet is rendered non functional for the life. It takes about 8 days to replenish new platelets.
 
That’s why to separate aspirin and other NSAID’s by about 4 hours. Let aspirin do it’s thing before the ibuprofen interferes.
 
Maladaptive clotting leading to a stroke is largely dietary in cause, the payback for a good life of cannibalism. Not that vegetarians are immune entirely but the incidence is much lower. It’s not so much the blood but in the cholesterol connection. More about this.
 
John

Jyorishvarii,
 
Here’s my take on the info you asked about. Long forking post...It is not a popular opinion for obvious reasons. Better do this and back off before I get busted for spamming the place or starting a flame war. So a series of pieces of a puzzle that should lead to a conclusion if I done presented it right..
 
Okay, regarding stokes and clots, what is the relationship with age…
 
There is probably some significant causality with age itself since all our internal set points start to lose focus over time, but the hemostatic system usually maintains integrity into old age long after other things have gone south and are falling apart. You are progressively deaf and nearly blind. Lungs and kidneys are shot. No teeth left. Bowels can’t move and every joint of the body is frozen with arthritis. But blood still clots like it should.
 
The main culprit in aberrant coagulation is cholesterol overload in a meat eating humanoid. Oversimplified claim but keeping focus on the aspirin/platelet/cholesterol axis.
 
Consider that we are vegetarian, or nearly so by our structure when we look at the bio physiology of other mammalian species around us that we have not yet driven to extinction... Corpse eating came about many thousands of years ago as an adaptation for survival. If we did not revert to cannibalism, we would not be here now. Smart move at the time. We just never got back to our roots, so the curse continues with all the bad karma, ailments, premature aging and premature death. (off my soap box for now…)
 
We didn’t really get our noses rubbed into the crisis of cholesterol damage until the Vietnam war, when thousands of our young kids were being sent back in body bags.
 
Cadavers were at the time on top of the medical food triangle. You can see how they have had to rethink this over time and come up with the new latest and greatest. Autopsies of the kids showed that their arteries were clogged as bad as a person in old age. Big shock and shakeup over what we thought was wholesome and good.
 
Reference the inside of our blood veins. Maybe not us here as we are already screwed up and damaged goods, but of a child not yet sludged shut by McDonald’s burgers. The layer in contact with the blood flow (endothelium) is a miracle matrix with a slickness beyond any teflon we have been able to produce.
 
Reference also the nature of what is in the blood to understand this. We got water and a lot of different chemicals dissolved down to the molecular level and a lot of big chunks of things in the mix speeding around to do various tasks.
 
Blood achieves what is called a “laminar flow” in a pristine condition. All kinds of blood cells, proteins, big stuff being shuffled around hi speed by circulation when the heart beats. The incredible endothelial interface is so smooth and resistance free that everything flies with no turbulence.
 
Reference that the body (liver) produces all the cholesterol we need, and cholesterol is absolutely needed for a lot of reasons. Because we were never meant to be carrion bottom feeders, nature has not supplied us with a feedback loop to cut down hepatic cholesterol production even in the presence of deadly levels of dietary intake.
 
Reference, maybe most important from the aspect of diet. Nothing dietary of plant origin has a single molecule of cholesterol. Everything of animal origin is filled with cholesterol. There are hi fat and lo fat corpses, but no lo cholesterol corpses. Here is where we get into trouble. Fun and frolic for a few decades until payback time.
 
Focusing on stroke, as the corpse load starts to plaque the arteries and veins, some things happen that are not too cool. First the endothelium is covered and the teflon smoothness is lost. Anybody who has seen the scopes of occluded arteries thinks a second time about that raw raccoon waiting for dinner. The presentation is ugly, like corroded sewer pipes with blobs and chunks of cholesterol building up on the walls. If these completely shut closed, like in the coronary arteries, then a heart attack drops like lightening and you are dead. It takes the meat build up of several decades to occlude more than 90 percent of the arteries before you start to feel pain in the chest and just cant breath right any more.
 
Getting back to the problem of stroke and reference to my previous tirade on platelets.
 
In the laminar flow model, we can bounce around thru life bumping into things, fall down, bruise a knee. Things still flow smoothly in the circulatory system with the trauma to platelets being still below the threshold for activation and clot formation.
 
When cannibalism covers the endothelium and the crud builds up into an ugly jagged terrain, laminar flow is lost. Turbulent clashes are happening unfelt in the body even if we are sitting in a chair eating beef jerky calmly watching Oprah. The body is getting the signal that we are being pounded by some excessive force and are probably bleeding to death. Don’t know where it is coming from, but coming from everywhere. Start forming clots to seal the leak.
 
End of the story. Another one bites the dust.
 
Got to say however that all is not lost if one gets right with Allah and abandons their evil ways.
 
There is a point where the cholesterol buildup, which is inflicting an inflammation response on the endothelium causes a terrible union of meat byproducts and your cells to mutate into “foam cells”. Now you done crossed the line. Any swami guru health spa is only going to do so much since you have carved your own epitaph beyond repair.
 
We used to think that cholesterol damage was set. All you could do after diagnosis was to slow down the damage. We since know with a glimmer of hope that the body can somewhat reverse the damage if the dietary patterns are changed to not feed the condition.
 
Got to duck and run after this rampage. I already feel the love.
 
John

thanks John-you should write for the W.H.O. or Mayo Clinic-they are my go to sites for advice but lack your literary flair.
cheers

Thank you Webbs...