If lowest possible round-trip latency is paramount, stick with RME or MOTU.
Round-trip latency is the sum of the following:
- ASIO input buffer
- ASIO output buffer
- The driver's safety-buffer (often hidden - this is the X-factor and not all units are equal)
- A/D D/A converter latency
At 44.1k, 64-samples equates to 1.5ms
Thus, at a 64-sample ASIO buffer size 44.1k... you've got 3ms for just the ASIO input and output buffers.
Add to that the safety-buffer and the A/D D/A latency... and you have the total round-trip latency.
Increasing the sample-rate does lower the round-trip latency... at the expensive of higher CPU use.
Doubling the sample-rate will cut the ASIO input and output buffers in half (latency wise).
You still have the hidden safety-buffer and the latency from the A/D D/A converters, so the figure is typically higher than half.