I use both Vir2 Electri6ity and Acou6tics - Yes; these are very complex instruments and not immediately user-friendly, but if you are prepared to spend the time tinkering with the keyswitches and controllers, they certainly provide accurate emulations of the real thing and my results have so far been most satisfying.
these are my only guitar VSTi's, so I have cannot make comparisons to other products. However, I suppose it is like adapting to any alternative control logic - you just learn to steer in a different way - oh, and you need a 109-note keyboard too (I use a 61 note, a 49 note and a NI Maschine combined)!
I hope Vir2 tweak the products further; articulated feedback, deselecting strings so that they play open in conjunction with three-note chords, out-of-phase pickup selection on the strat, possible different chord structures for different tunings (DADGAD etc).
Perhaps I should just loearn to play the guitar better, eh?!!!