My plan is to let my next machine build, at whatever point in the future, play the cleanup role. With samples on a secondary drive, the potential space savings isn't worth the time/trouble for me to bother with uninstalling.
And as AT said, there is always the chance an older project will get revisited.
IIRC, you should be able to hide (exclude) the old versions via Plug-in Manager to declutter your instrument select lists.