Not to worry, those conversions aren't a concern. No data is lost converting from 32-bit to 64-bit. Going the other way is necessarily going to truncate the least-significant bits, but it's like asking for ten pounds of peppered bacon and having half a peppercorn fall off during wrapping. Nobody's breakfast is going to be ruined.
What an effect does when bypassed internally is up to the plugin vendor, so there could conceivably be a difference between hitting the Bypass button on the plugin versus disabling it via the fx bin. In the latter case, data is not sent to the plugin so there's no way for it to affect the signal.