I always use volume envelopes in the tracks for pure volume changes.
Adjusting the levels in the synth can at times affect the sound's timbre.
Generally, I find that I leave the tracks at a specific level..... depending on what I need. Sometimes they are 100% out of the mix. I rarely let something just play..... (with exceptions like acoustic guitar, piano, bass & drums) at the same level all the way through..... in my music you will notice things coming and going throughout the song. Fills, solo's parts to increase the energy and feel are all enveloped in and out as needed.
see this example..... notice everything is surgical in nature. precise edits.... no multi-node movements.
Track 10 B3 is low but the same level
Track 11 Piano is all the way down.
12&13 are playing the fills by edits.
The song:
http://soundclick.com/share.cfm?id=11971116 and you are looking at the first verse of the song, and the edits are the piano fills you hear.