On the few occasions I've tried Sleep Mode I discovered that not everything would Wake Up properly, so I ALWAYS switch everything right off at the end of a session.
I have my Computer, Audio & Video Monitors and Interface connected to a UPS.
The UPS, along with all the rest of the peripheral gear (rack equipment, lighting, minidisc player, cassette deck, Mic Pre etc) is connected to the mains by way of standard distribution blocks in a Star System
Once the monitors & pc are powered down, I simply shut down the UPS, then hit the wall switch.