noynekker
Personally, I prefer non-destructive editing while I'm creating and mixing, then the region FX will all get rendered when ready to move on. I've noticed lots of un-rendered Melodyne clips simply makes the Sonar project file much larger. I've never had any issues with Melodyne that I can attribute to memory limitations, and when I rarely do, it must be time to render.
If you burn all your bridges, you can't get back to where you were.
Always interested it what people are doing unconventionally.
I always clone the track Im working on at least once, to work on and have at least one working track to copy changes into when I need to, so somewhat non-destructive.
It does make projects much larger if you haven't bounced, also it accumulates a lot storage memory, even after bounced, on C: drive in My Documents/Celemony/Separations folder, for polyphonic stuff, you can delete contents if your looking for some room on a SSD you may find some here, first time I did it I think it was around 50 GB, it will regenerate saved but un-bounced polyphonic data back into folder when opening a project. You pretty much need latency set to at least 1024 samples for it to function properly, I always have it set to 4096 anyway for mixing and editing, so dont have issues either.
Otherwise, save often, especially if your leaving Melodyne active with un-bounced edits, or you may loose all your editing work if/when it crashes un-expectantly, or expectantly, LOL.
Cheers