I think that if you use Overture, having one decent orchestral library with instruments that are pre-mapped to something other than GM is a must have.
If you don't use Overture, then there are a lot of other options out there. But Amadeus looks like it should be useful for just about anybody.
That's one thing I like about Notion, is that it comes with a built-in orchestral library. It's not the greatest, but it is fully integrated, and the sounds are better than a stock GM sound font library.
I was checking into Garritan GPO 5, but it appears that full compatibility with Overture and Notion was lost in the upgrade from GPO 4 to GPO 5. I have heard that it sort of works with some tweaks, but is no longer fully plug and play.