Sounds system/project-specific. Need more info:
- Have you rebooted recently?
- What interface, driver mode and buffer size? Any changes recently?
- If ASIO driver mode, is 'Use ASIO Latecny enabled in Record Latency Adjustment, and/or do you have a non-zero Manual Offset entered?
- Does the looped region start at 1:01:000, and if not, are you starting recording at the loop start point?
- Are the loop points snapped to measures/beats?
- Is punch also enabled?
- Is metronome count-in enabled?
- What tempo? Any tempo changes?
- Direct or Input monitoring?
- Are there any PDC-inducing plugins in the project?
- How much error/variability are we talking about in samples?