yes. in certain cases e.g. when manipulating tempo track and not wanting clips to move with it or when having completed editing a multi mic'd drum kit which I don't want to touch anymore (especially by mistake as with clip starts a few ticks before the measure this is really hard to verify if you have e.g. unintentionally group selected and nudged a tick or 2) ...
BTW - clips with locked data or locked position are excluded from ripple editing (they are locked afterall) so you might get surprising results if you don't think first what the consequences of both options at the same time will be (all seemed to work fine when gave this a try)