I went from a heavily tweaked win7 (everything off that is not needed) to win10 (in-place upgrade).
 
I wonder if anyone did any tweaks or customizations for the sake optimum audio performance? Not sure if I would need / want any ... but also not sure if the update did reset all the tweaks I had in place ???
 
I did set the updates to "notify only" and disabled windows defender as the DAW is offline 99.8% of the time.

Not really. Most systems are powerful enough to where tweaking is not necessary.