Since my last post I have had this happen again on a different PC with a different USB device, starting to think this is either a project issue or a SONAR issue. It happened on my home PC with the Focusrite using SPLAT on Win 10 64 bit. And now just 2 days ago on my work PC running SONAR Professional on Win 7 64 bit. This was using a Steinberg USB device. Had to shut down SONAR with task manager, reopened the project and everything was fine. But it's odd that the OP has this issue, and I've had it as well on different PCs. Something to keep an eye on.
One thing I do with all versions of SONAR is under Preferences/Audio/Playback Recording is set the Fade on Start and Fade on Stop values to about 10-15 ms. Wonder if that has anything to do with it.
PS I apologize to Focusrite for blaming their product.