Straight from the horse's mouth. Bob knows how to record guitars!
The general rule for any instrument is that you only record a stereo track when the source is truly stereo. A guitar pickup generally is not stereo, and most stompboxes are not stereo. The exception would be something like an inline stereo delay or reverb - a unit with two outputs. Anything else, stay mono.
But even if you have a nice stereo effect on your pedal board, you might elect to bypass it in favor of adding the stereo effect
after recording. You can then record in mono as nature intended, but still add some cool stereo effect such as a ping-pong delay or chorus afterward - in the box where you can experiment and have full control.