That message shows when another audio driver takes over the audio driver you where using. So to me this is simple. Your main audio is the Delta 1010 which you normally should use ASIO mode.
But because you also are using the line 6 you therefore use WDM mode which supports using 2 audio devices. Forget all those other devices, they are not audio and do not come into play.
SO this is a simple matter of losing the driver for the Delta.
If you not using it, disconnect the line 6 and switch to ASIO mode for the delta and see if this goes away.