I've been using a US-16x08 for quite some time. It is/was finicky for me in some of instances.
The BiaB folks had to make a change in their ASIO code for it to work properly with BiaB. It works fine now.
AmpliTube and Sample Tank preset/instrument changes will frequently introduce a huge delay. In SONAR, toggling PDC after the change gets it back. In Reaper opening/closing prefs>devices gets it back. I bought a UMC404HD to compare - zero problems with the 404. The downside is the output levels of the 404 ... <sigh>
WDM mode in SONAR does NOT work correctly at all. I have not tried WDM with the 16x08 in other software.
The above problems with IKM software are an annoyance, but not show-stoppers as everything else seems to work fine and I LOVE the flexibility of the 16x08. I'm enduring it until my next DAW, hopeful that updated chipsets will improve the situation. If it's still wonky at that point I'll probably ditch the 16x08 and replace it with an I-don't-know-what.
The recent driver/firmware updates didn't result in any real changes good or bad.
It's entirely possible that there is something wrong with your 16x08 hardware.