I believe you can still use plug-ins that were coded for the UAD-1, but I'm not sure about buying them, so you'll probably be limited to the plugins that came with it - which is still a pretty outstanding collection!
I still have a UAD-1, and I've been meaning to build a machine with a PCI slot so I can use it again. Of the bunch, the Nigel plugin was probably the one that I'd like to have access to again. But the rest are still pretty cool.
Contact UA support to get the straight scoop!