Per online specs, the Multimix 8 has 8 analog inputs to its analog mixer section but only one stereo digital interface input to the DAW via USB. If you pan the two analog inputs hard left and right, you can record them to two mono tracks with inputs set to left and right channels of the stereo interface input.
It's not clear how you're getting the Skype signal into the mix, but, unfortunately, you're not going to be able to record 3 inputs simultaneously with only one stereo input to the DAW from the interface in any case.