Altering a small one instrument or voice clip will render much better results than altering the entire stereo mix of a 5 minute song. For that I would use an app intended for such.
 
BTW, It's not always about "fixing" something. Sometimes you're just after a different effect.

I actually make full backups of my projects before using Melodyne and I'm very aware I can clone the track before creating the fx region. This doesn't solve my issue of making small tweaks after listening with fresh ears. I don't want to have to start from scratch. I've over corrected a note or two before where it doesn't sound natural in context and it's nice to be able to back off on the correction (I'm talking errors that 90% of the population wouldn't even hear anyway).

So if I'm working on an fx region and my sonar crashes after an hour of fixing a track, I should just accept anomalies on that region when I re-open Sonar? So it's not enough that I save every 5 minutes but I should render my clips that often as well?

I actually don't even use Melodyne much anymore. The algorithms were more transparent back with 2 than they are now in 4. Just google "Melodyne 4 disappointment". I'm not alone with this opinion. I keep hoping Celemony will fix studio 4 to the quality I enjoyed previously.

Hi,
In platinum, how does one enable Create Region FX on a clip?  Right-clicking a clip, Region FX>Melodyne>Create Region FX is not enabled nor any other Melodyne menu item.

Is Melodyne in your VST scan path?

I'll check.

Scan path looks good.  Only way I can use the tool is to play it in with transfer.

Try reinstalling Melodyne and make sure the VST3 version gets installed.

OK, thanks for the advice.

Scan location for Melodyne VST3

Program Files\Common Files\VST3\ Celemony\melodyne.VST3

Yep, that's the current location.  Thinking of reinstalling at above suggestion and see if that resolves, then rescan.