JohnKenn
Jim,
Can you clarify a bit more since didn't understand some of the intention. Always trust your advice. Never been on this part of the forum and was about to open a thread. Looks like vdd is dealing with the same issue.
Qualitative assessment is that I have an old quad core XP 32 bit rig with a PCI M-Audio 1010 LT sync'd to a 2 channel M-Audio 2496. This performs well, 10 channels, but obsolescence has me up against a wall and will have to upgrade the system at some point.
Have been beta testing a synth that is a real CPU hog but performs well on the XP rig.
Have a 64 bit win 7 i7 laptop 6G RAM connected via USB 2 to a Presonus 22VSL box. The thing sounds like a popcorn popper unless I increase the buffer to over 2 sec. All drivers current.
The fire power of the laptop is overshadowed by the bottleneck of the USB 2 connection. Feel like hard wired PCIex slot is the way to go on a new computer.
Any recommendations on a PCIex with 8 channels.
Many thanks,
John
Hi John,
FWIW, I'm going to repeat what others have said.

The problem isn't USB2's bandwidth.
Eight channels of I/O is nowhere near saturating the USB2 bus.
FWIW, I run a RME Fireface UFX (which is a USB2 unit with 30 channels of I/O).
I can run substantial loads glitch-free at a 48-sample ASIO buffer size.
That's 4.3ms total round-trip latency at that 48-sample ASIO buffer size 44.1k.
Lots of throttling going on to keep CPU temps in check with most laptops.
Have you measured the laptop's DPC Latency?
My guess is it's pretty high. If that's the case, no audio interface will work well at lower ASIO buffer sizes.
Lynx, MOTU, and RME all make excellent PCIe audio interfaces.
Lynx doesn't make a PCIe unit with 8 channels of analog I/O.
MOTU's PCIe 424 controller can be used with the 2408mkIII. Converters are a little long-in-the-tooth... but performance is good.
RME's HDSPe with Multiface-II performs well. You may have trouble finding this new.
MOTU have announced true "PCIe via Thunderbolt" drivers for their new AVB audio interfaces.
You'll need a motherboard that supports Thunderbolt 3 via USB-C port... and you'll need to run Win10.
This combination will yield performance equal to PCIe units. That's the whole point of Thunderbolt (external access to the PCIe bus).