Hi Jan,
It would help if you could give some specific details on your machine (i.e. which audio interface, RAM, CPU, MB (as much info on your system) etc...). Are the drivers for your soundcard updated? Do you have Wifi enabled? (that can definitely cause latency/disturbances).
(I may not be the one to give you a solution, but this info will certainly help others that chime in).
If nothing else, consider this a free Bump!! :))