As I've posted, my system has been unstable for a few weeks. Projects freezing and crashing when being opened and right after rendering, etc.
I'm using an Audient iD14 and a Focusrite 18i20 (what can I say, I'm a sucker for a lower-case "i")
Yesetrday, just to see what would happen, I tried using WDM drivers with my iD14, and performance and stability have been MUCH better. I was actually really surprised that WDM drivers are compatible with the interface at all. It also works well with MME on my laptop!
I'm hoping that an upcoming Windows update (or CW) will resolve the issues. I've already re-installed all my software, so the problem lies elsewhere.
I'm just posting this in case it helps someone else.