Reminder: when using Melodyne's polyphonic algorithm to convert guitar to MIDI....

If you're using Melodyne's polyphonic algorithm in the Editor and Studio versions to convert polyphonic guitar parts to MIDI (which is an incredibly powerful and useful way of creating synth parts if like me your skills lie on the fretboard and not the keyboard), then be sure to turn your guitar's tone pot all the way down when recording the guitar part. You end up with a much duller tone which does not have anywhere as many of the kind of harmonic content which Melodyne misinterprets as notes. As a result your MIDI is far more accurate and requires less editing. 
 
I keep forgetting this and end up spending ages deleting the bad notes. Tonight I recorded quite an intricate, fast piece of fingerpicking with the tone pot all the way down and I was really blown away by how well Melodyne converted it. I should think this advice also applies to the melodic algorithm as well, but it's especially useful for the polyphonic algorithm. 

Great info. Thanks for sharing. 

I find Jam Origin's guitar to MIDI software also tracks better using the neck pickup with the guitar tone rolled off. Not surprising I suppose, if you look at an electric guitar's output in an oscilloscope the waveforms are all over the place with the tone control(s) wide open. Loads of harmonics that keep varying in frequency and relative strength. Rolling back the tone and using the neck pickup provides a signal that's much more focussed on the fundamental frequency.

The same "trick" works well with Hendrix-style analogue octave fuzzes.