Removing DC Offset Usage

Reading through the 1800+ page Sonar Manual, I came across a feature called "Remove DC Offset."  Sure enough, looked in the menus and there is an option that I had never paid attention to before.  So I understand that the analog audio part of my siginal may not have been processed by a perfectly biased amplifier at some point.  It makes sense to me that I should probably process all of my analog through this process. 
 
Can anyone recommend when I should do this, what setting would be a good starting point, and what do I need to watch out for when doing this?
 
Thanks.

If your DC bias is high enough to actually be a problem, it's likely an indication of a defective ADC, preamp, or microphone. (It could also a badly-coded plugin or soft synth - I have some clipper plugins, for example, that clip asymmetrically, causing DC offset.)

Fortunately, in the digital realm it's rarely a problem and not worth worrying about.

In fact, the reported DC offset probably isn't even accurate, since there is no standard threshold between true DC and very low frequency content. But that's OK because it has to be unusually bad before it causes any audible harm.

At any rate, both DC and VLF components are normally removed in the mastering stage. If you're like me you already use a HPF on the master bus to kill everything below 30-40Hz anyway, which will also take care of any DC bias.