Roland released a W10 driver for the UA-4FX.

If anywho out there uses a Edirol UA-4FX (a great little box though without drivers it won't power up via USB and there is no pass-thru) there is an update for the W10 drivers. (You're welcome, though Roland did the actual work.)  I prompted Roland to update their drivers and they were really good about it. So, for those attempting to use W10 (why I'm not sure yet, but it is early days), be sure to get the new UA drivers. They're they same (no updates, thank heavens), but will install now.  It's a bit ominous that the early process of disabling the 'Driver Signature Enforcement' option has been (apparently) removed from W10, so one can no longer force W10 to load the W8.1 drivers (no matter how well they were working!).