1. Verify that you have
driver version 1.02 and firmware version 1.01.
2. Re-install the drivers (not the firmware if it's up to date). Upon installing Windows 10 (an in-place update from Windows 7, not a clean install), I had to re-install the drivers before the interfaces worked properly. This was also the case with a 4x4 I tested.
3. Which version of SONAR are you using?
4. If you're using a hub, plug the interface directly into a motherboard USB port. Actually this is good advice for any audio interface, not just the 2x2.
5. Are you doing real-time or fast export? It may seem counter-intuitive, but fast export is the most reliable option because it compensates for potential issues with real-time playback and latency.
6. Try with the 64-bit double-precision engine turned off. Some systems don't like it.
I use the 2x2 with my HP laptop at Gibson, and the 20x20 at my home studio. Crashes happen rarely, maybe once a month if that, and I use SONAR every day. I also have been doing a ton of exports lately because I've been mixing down projects to two-track masters, and no problems with crashing.
FWIW because TASCAM and Cakewalk are both owned by Gibson, I know for a fact that SONAR was tested extensively with their interfaces, starting with the 2x2 and all interfaces since then. We'll figure it out.