Huh? It is usually the OS system, so if it is Windows 7 then about anyone made except firewire ones. If it is Windows 8 then you will have to find out if it truly has drivers that really work. If it is soft synths then the computer will not be so fast for many of those.
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http://www.sweetwater.com..5--USB_Audio_Interfaces About any normal channel USB 2 device will work, but not Firewire unless you really want pain because computers usually do not have a firewire port and that takes a card for the port and usually then your video card unless you have 1X speed pci-e slots also. Most computers have 1 - 16X pci-e slot for a graphics card and then the rest can vary but may have a couple of 1X (like mentioned) pci-e cards for audio, or whatever will fit in there.
USB hooks up externally so only a USB 2 port is needed, although USB 3 ports may be compatible, but better to use a USB 2 port on the computer. Of course with mouse nowadays, and other devices using USB ports, then hope it all works together as well as any other unit like a guitar effects BOSS or something or other unit for guitar - persay.
If it has Intel Graphics on the motherboard, then disable that and the on board (Realtek) sound card in the BIOS, and buy a Nvidia Geforce card (doesn't have to be one of the newest ones) or a Radeon card (except I usually like Geforce drivers for the graphics card better).
??? I have a RME Babyface and it works fine for what I do.
http://www.sweetwater.com/store/detail/Babyface/and RME has drivers that work and also now Class Compliant Mode.
http://www.rme-audio.de/forum/May not understand how it works in the first place with TotalMixFX program but then it is automatic and that program is for routing the signal and monitoring the signal. Also includes Digicheck and by that program, you can analyse the sound in each channel but then it has a manual that some people find hard to read and make any sense out of.
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Other people use different manufacturer's units.
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You can spend more or less and depending on how many channels you want and need.
post edited by spacealf - 2013/06/18 19:34:54