RE: Windows Vista & Home Studio 4xl
No it's not compatible, no there's not a patch. you have to upgrade to SHS6(or SHS6XL).
having said that, there are some folks who have gotten it to work under Vista. some have gotten it to work fully, others have had limited capability, but since cakewalk doesn't claim that it's vista compatible, you won't get support from them on that platform anyway, so i would just upgrade.