Hi, and welcome to this forum Joe. As mentioned earlier, more info is required. Can you access your audio device in Preferences (P), Audio, Devices? Do you have share drivers with other programs enabled in Preferences (P), Audio, Playback and Recording?
All the best.
Ken Nilsen
ZarggBBZWin 10 Pro X64, Cakewalk by Bandlab, SPlat X64, AMD AM3+ fx-8320, 16Gb RAM, RME Ucx (+ ARC), Tascam FW 1884, M-Audio Keystation 61es, *AKAI MPK Pro 25, *Softube Console1, Alesis DM6 USB, Maschine MkII
Laptop setup: Win 10 X64, i5 2.4ghz, 8gb RAM, 320gb 7200 RPM HD, Focusrite Solo, + *