I like having a buss powered usb soundcard, but I don't think any of them are 4 mic in. I've had the Quad for about a decade, it's serves me well. I think it picks up a little noise on inputs (groundlift or or off, but there is no ground in this country or from my laptop), I also get a bus powered shock from my guitars. I came from a M-Audio FW1814 that was nothing but problems, accross 3 TI FW chipped laptops, so I've stuck with the Quad and accepted the quirks, I do miss having a separate headphone and speaker level. Having to reach around the back of my powered monitors is a pain.
I intend on switching to a Focusrite 214 in the future (not available in this country) which will give me the buss power 4 AD converters, and the headphone level. I hope no more shocks (which I tiny) an a cleaner chain. It still doesn't have 4 mic pre amps, (just two) I guess that's too high for a buss power supply. But I only have two mics. But should I want to use mic and DI, or finally get around to buying matched pair, I have back in the UK to rackmount channel strips from almost 2 decades ago (Focusrite Tone Factory and Envoice Mind-dprint), that I never got around to selling and probably wouldn't get much for. But they were cool nd look like may be useful in future