Heat will definitely play a factor (I saw this with intense read/write operations), and the memory cells will degrade over time as well, especially if the "write" area is a small percentage of the drive. Not sure if this will be much use but I noticed two things with my old Patriot Wildfire (240GB).
1) Internally it will not throttle itself, so any massive installation packages (specifically DimPro installs) would blue screen it from the internal heat load. I ended up having to manually unpack those packages with 7zip prior to installation, since the double whammy of back-to-back intense operations overheated it about 50% through the installation process.
2) I had the SSD go dark to the BIOS like three times with the oddest "fix" ever. Booting from a Win7 recovery disc, I would choose the repair option, it would run a bit then say "The version on disc is not compatible with the installed version..." So I exited, rebooted, and the BIOS magically recovered (really odd).
There are some utilities to check an SSD health, and I ran those with nothing found. The cells will degrade over time (I think my benchmarks degraded about 10% in 6 years with it), so in preparation for the inevitable I bought a replacement and imaged that over. I did not notice any similar issues with the new SSD (Samsung 850 EVO 500GB). A few months later I bought a new machine and stole the Samsung to be the D drive, and threw the Patriot back into the Win7 machine. Ironically, the Patriot still outbenched the Samsung using Samsung's software.
The EVO's go on sale fairly frequently, and the cloning tool worked like a charm once it installed (IIRC, the upgrade to it didn't take, so I ran the version it initially installed).