One of the things I had to ask the S1 community, and hopefully there's a good answer: Can multiple Layer events/clips be played simultaneously after comping, like you can do with Sonar's Lanes? So far, I don't see a way other than moving clips/events to new tracks, but I gotta ask. The key, 'K' was my friend. Also, note, once you move a clip into a Layer in S1, you can no longer move it. I really don't get that. What's the point of freezing it like that?
I also noticed, S1 does a much better job at recording multiple takes of many tracks simultaneously, creating new Layers on each take. Sonar always struggled here, requiring new Projects for each take in many cases.
S1 also has Cue Mixes, assignable to multiple outputs! That's pretty awesome, if the latency is low enough. Obviously, if you use their hardware interfaces, you get the real benefit.
And someone PLEASE convince Presonus to let us customize color schemes! hehe. I could totally go for making a Blue Aston S1 color scheme.