Great thread: imho, to brainstorm slightly:
... for personal or artistic purposes or 'getting out of the box' (as most of you hinted)
... 'Get the vox out of the central clutter for clarity-separation
... for drama or attention
... with a balanced 'force' on the opposite channel
... with choir vocs, counter vocs, etc. on the opposite channel
... with dialogue vocs, duets, or multi-vocs, etc.
... Methinks it OK in the car where panning gets jumbled with ambient traffic rumbles (to my ears), if the car becomes my target listening environment.
... with some mixes that are beatz or snare dominant; perhaps vocals could be hard panned for some of these and sound great in some environments ... with 'L-C-R' schemed mixing.
... I suppose the Beatles and other psychedelia singers really didn't mind hard-panning when their music and vocals wanted 'separation'. The listener could listen to the words more directly (I think).