That's one of the conclusion I came to when it comes to amp sims and software - there is no single solution for me. Which is why it can be just as cumbersome and even worst than recording a real amp.
Every amp sim I own has been usable with excellent result in x number of situations -
all of them! My POD 1, Guitar Rig, Amplitube, GTR, S-Gear, Line 6 Spider IV, POD Farm, etc...
And all of them have failed to work for me, even more often. I can't neglect to factor in my lack of patience, which only gets worst when you have hundreds of different solutions a mouse click away. It's just so easy to move to the next thing.
On the other hand, with a real amp, that doesn't happen as it's very easy for me to dial in and capture something I like. And it has that sustain, that density which just isn't there with sims.
But things being what they are, I'm looking forward to tracking with the POD HD again, this time running it through the new Mackie board. This means I'll be able to take advantage of a much needed low cut and maybe dip a few things here and there live, on the way in.