If you're using your DAW as your livelyhood, I highly recommend contacting Jim Rosebury or Scott at ADK. They're the DAW guru's here and are exceptional at what they do.
If you're a hobbyist (like me), then building a DAW by yourself gives a lot of control in using the hardware components (future compatibility) and also the satisfaction of accomplishing a stable build. Of course, there's a bit of research on your part that needs to be done, but totally worth it IMHO.
If you're buying an off the shelf PC, (like Mettelu said) they use the cheapest components. Of course, you "might" get a very stable system off the shelf, but when you consider all the higher end auido (software & hardware) that you've invested into producing music, I'd certainly want a solid machine to house all of this.