I would say from a business prospective it's going to hard for any one to go up against Kontakt. Motu MachFive is about the only thing offering them a challenge at the moment. Maybe Magix will do something now they have bought Independence.
If there is going to be a next generation of Dimension Pro it should have (IMHO).
Scripting.
Key-switching
Graphical sample mapping for users to create their own instruments easily.
Involvement of third party content developers, and more than just DSF.
Where Kontakt wins hands down at the moment is not what NI puts out but the huge range of third party content from the free and the whacky to the expensive and the sublime. Cakewalk working with the likes of Orange Tree, Hollow Sun, Boulder Sounds and Sound Iron, there is an interesting concept!