I have the stock Win 8 Pro 64 bit installed with Sonar X2. Although Win 7 64 bit is still my "production" system, I've used the Win 8, without any tweaks and all seems to work. However, I don't do a lot of MIDI or use samples so it may make a difference.
Do not try to use the DPC Latency Checker on Windows 8. The checker is not compatible with Win 8 and will give false latency spikes.