You will likely never exceed the USB transfer rate in a normal project, so I would not do this just because of it being Pcie. But hope you figure it out.
All the best.

Zargg71
You will likely never exceed the USB transfer rate in a normal project, so I would not do this just because of it being Pcie. But hope you figure it out.
All the best.

Ok thanks for the feedback Zargg... I'm going to tinker a little with the PCIe anyway.... someone mentioned in an amazon review that they successfully paired it with their layla 3G PCMCIA card... dunno if s/he achieved 24/96 or if it is even the same PCMCIA card as the layla 24. Can you point me in the direction of the conversation on this site or elsewhere about PCIe added noise or other issues? 
 
What about a PCMCIA to PCI adapter for the desktop. Then I'm not using a PCIexpress but rather just PCI.

Good luck, and let us know how it goes.
All the best.

If it were me, I'd consider the Echo Layla a lost cause. Take a look at the Echo Audio product page and you'll see that they've discontinued all pro audio products and no longer support them.
 
 

^^ I agree with this. Had an Audiofire 8 (a couple of years, which I bought second hand) which became unstable, and the on / off button worked occasionally. And then I saw that they discontinued their audio division. Great product, but not forward compatible.
All the best.

I'm still using an M-Audio Delta 44 (plus a Presonus Bluetube, b/c the Delta doesn't have it's own mic pres) that I bought in, like, 2003. It works fine with Windows 7, but is not supported for 10. 
 
I've been hesitant to upgrade b/c it's hard to find affordable PCI or PCIe interfaces these days and USB is significantly slower. I get very little latency with the Delta when recording through amp sims in real time, and that is absolutely crucial to my enjoyment of the whole home DAW experience. Is the consensus these days that USB can, in fact, support low-latency real-time tracking through, say, Amplitube?

papercut
I'm still using an M-Audio Delta 44 (plus a Presonus Bluetube, b/c the Delta doesn't have it's own mic pres) that I bought in, like, 2003. It works fine with Windows 7, but is not supported for 10. 
 
I've been hesitant to upgrade b/c it's hard to find affordable PCI or PCIe interfaces these days and USB is significantly slower. I get very little latency with the Delta when recording through amp sims in real time, and that is absolutely crucial to my enjoyment of the whole home DAW experience. Is the consensus these days that USB can, in fact, support low-latency real-time tracking through, say, Amplitube?

The best you can expect is around 4ms or so latency on USB with a fast machine - good enough for tracking.
 

mileskb
 
So am I reading that a Layla 24/96 will NOT work under Windows 10?  I'm going to try it in a couple of days, but I have a bad feeling, and I think I know the answer.
 
So the next question...  what's out there today that can record and playback at least 8 channels, and supports MIDI and S/PDIF ?  

Windows 7 drivers should work.   My M-Audio FW 410, AP 192 are working on a Windows 10 system (all legacy) by using the W7 drivers. 

It's unfortunate that Echo went the way of >>All pro audio products have been discontinued. 
I used an Echo Gina 24 for years & years after I upgraded from the Soundblaster era.
 
Recorded, mixed & published two CDs (regional distro) that rock solid bad boy!
The first one was with Sonar 1 - when Sonar was just Sonar.
 
 

no love yet on my layla24 / osx 11.1/ CardBus to ExpressCard adapter. I installed layla24 osx 1.6.1 driver just fine and from what I have read it is OSX coreaudio compliant. In system preferences > audio Midi setup , there is no recognition of the input. I believe I would see the input here before any of the software - eg ableton, cubase, audacity...
 
Any ideas? I could try my win7 build. Kinda disappointed I haven't even gotten the input recognized. I think maybe I'll update to OSX 11.1.3 as people reported audio equipment issues before that update.
 
Edit: figured out that layla24 does not support intel processor on os x only power-pc processor.