I've got 6 GB and would be moving to 8 GB.
I have Omnisphere and Morphestra is coming soon. I use Orchestral Essentials, BFD, other stuff you see below, and lots of effects. I'm sometimes up to 86% ram usage, or more. I could hit the ceiling if I get much more ambitious. So far, its been ok. But I want to have room to grow if needed. Wii 2 GB really make a noticeable difference? I'm thinking it should at least create a margin for some sonic elbow room. I'd like to own and run some choir libraries.