Go to this site to choose your chip
http://cpubenchmark.net/high_end_cpus.html They rate the biggest bang for your buck. When I built mine it was the 2600-K. K being overclockable style chip.
Choose your motherboard wisely due to the fact the PCI sound cards are some of the best (fastest).
However, my Lynx card is PCI not the new PCIe. So I had to choose a legacy Mother Board that had that slot.
Also, I don't recommend building a mini tower anymore. My build was a mini tower because it fits in my insulated cabinet by my desk to keep the fans quite (its a ported cabinet for fresh air). To hard to find parts like chip cooler fans for overclocking etc....
Take a close look at using SSDs. It's the wave of the future. Sonar's automatic backup and windows happens so fast- I don't even see it happening at all.
Also, think about a good video card for multi monitors. Its all in windows 7 now and you don't even need any other software to run them, just the video card driver.
Just make sure you start on paper first. everything has to say that it is for whatever part you are matching. Chip > Motherboard has chips socket> case fits Motherboard> etc...etc....
And like you probably have learned over the years get the most you can afford at the time because the software will keep getting more and more complicated (if history stays on course).
I saved pretty good $ building my own but it took a long long time. When you count research research, research and ordering with a return, etc...etc... ; was it all worth it- yes because now I feel like I know a lot more about computers.
P.S. Oh and be very careful. For example; did you know that Ram sticks all have to be a matched set? I didn't.
Hope this helps